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Artwork for Innovating Tomorrow's Medicine

Innovating Tomorrow's Medicine

Jeff Trickett
Cytisinicline
Nicotine Dependence
Duchenne Muscular Dystrophy
CRISPR
Biotech Leadership
Achieve Life Sciences
Smoking Cessation
Vaping Cessation
Messenger RNA
Biotechnology
Acurion
Immunology
Public Offering
NDA Approval
Syrna Therapeutics
Clinical Trials
Neurodegeneration
Cancer
AI In Healthcare
Oncogaze

Dr. Jeff Trickett is a neuroscientist, biotech strategist, and author. He hosts Innovating Tomorrow’s Medicine, a podcast highlighting the people and ideas reshaping the future of healthcare. He created the show to go beyond the headlines with honest conversations from biotech founders, researchers, clinicians and investors who are turning bold ideas into real-world impact. His goal is to discover... more

PublishesWeeklyEpisodes17Founded6 months ago
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Life SciencesScience

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Artwork for Innovating Tomorrow's Medicine

Latest Episodes

What if we could stop disease-causing proteins before they're even made—using small molecules to target their mRNA?

David Weitz, CEO of Syrna Therapeutics, is pioneering exactly that: 3D structure-guided drug discovery for mRNA, coupled with covalen... more

What if we could silence disease-causing proteins not by targeting the protein itself, but by preventing its mRNA from ever being translated—using small-molecule drugs?

In this episode, David Weitz, Co-founder, President and CEO of Syrna Therapeutic... more

What if you could know before a clinical trial which patients will respond? Not after Phase 2 fails. Not after spending $50M. Before you even start.

In this episode, Pilgrim Jackson, CEO of Yatiri Bio, shares how his company is using proteomics to p... more

What if you could know before enrolling a single patient which ones will actually respond to treatment?

Pilgrim Jackson, CEO of Yatiri Bio, is using proteomics to predict treatment response in AML and ovarian cancer with 100% accuracy so far—potenti... more

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Recent Guests

David Weitz
Founder and CEO of Syrna Therapeutics, biopharma leader with over 25 years of experience
Syrna Therapeutics
Episode: Targeting mRNA with Small Molecules: David Weitz, Syrna Therapeutics
Pilgrim Jackson
Co-founder and CEO of Yatiri Bio
Yatiri Bio
Episode: Predicting Patient Response Before Trials Start: Pilgrim Jackson, Yatiri Bio
Rick Stewart
Co-founder and CEO of Achieve Life Sciences, experienced leader in biotech focused on nicotine dependence treatments.
Achieve Life Sciences
Episode: Cytisinicline and the Future of Nicotine Dependence: Rick Stewart, Achieve Life Sciences
Sheila Gujrathi
Biotech entrepreneur, executive, healthcare investor, and drug developer with over 25 years of experience
Episode: Sheila Gujrathi on The Spiritual Foundation of Biotech Leadership and The Mirror Effect
Rick Fultz
CEO at Acurion, with extensive experience in life sciences and commercialization.
Acurion
Episode: Cancer Precision Medicine with real power: Rick Fultz, Acurion
Courtney Young
Founder and CEO of MyoGene Bio, with extensive experience in muscle disease research.
MyoGene Bio
Episode: CRISPR Meets Duchenne: Scalable, Precise, Disruptive - Courtney Young, MyoGene Bio
Stanley Lewis
Founder and CEO at A28 Therapeutics, with over 25 years of experience in clinical research and drug development.
A28 Therapeutics
Episode: Lytic Peptides: The Ultimate Cancer Weapon: Stanley Lewis, A28 Therapeutics

Host

Dr. Jeff Trickett
Host of a podcast focusing on the future of healthcare and innovative medical solutions, with a background as a neuroscientist and biotech strategist.

Chart Rankings

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Talking Points

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Targeting mRNA with Small Molecules: David Weitz, Syrna Therapeutics
Q: What do you see as success for Syrna in the next three to five years?
We want to achieve our clinical candidate and establish partnerships to expand our pipeline and insights in the RNA targeting domain.
Targeting mRNA with Small Molecules: David Weitz, Syrna Therapeutics
Q: What are your thoughts on leadership in biotech?
I fundamentally think of myself as a team member who picks up all the slack.
Targeting mRNA with Small Molecules: David Weitz, Syrna Therapeutics
Q: How do you ensure selectivity for disease causing proteins?
By targeting structured domains that are stable and persistent, we gauge selectivity based on binding characteristics and diversity of compounds.
Targeting mRNA with Small Molecules: David Weitz, Syrna Therapeutics
Q: What makes a messenger RNA domain drugable, and how do you validate these sites?
Understanding the target's nature and using structural biology to confirm stability and persistence are crucial in identifying drugable domains.
Targeting mRNA with Small Molecules: David Weitz, Syrna Therapeutics
Q: What has been your journey in establishing Syrna Therapeutics?
I started Syrna because I believed that targeting RNA is the next great small molecule target and it is inevitable that people will find a path forward in this field.

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Frequently Asked Questions About Innovating Tomorrow's Medicine

What is Innovating Tomorrow's Medicine about and what kind of topics does it cover?

Conversations on healthcare and biotechnology take center stage, showcasing innovative leaders and their pioneering ideas shaping the future of medicine. Episodes frequently address themes such as drug discovery, advancements in gene therapy, patient-centric healthcare strategies, and innovative technologies driving medical progress. The discussions aim to reveal transformative insights from experts in the field, exploring topics like messenger RNA methodologies, AI in cancer diagnostics, and novel biopharmaceutical approaches focused on addressing significant medical challenges. What sets this podcast apart is its emphasis on authentic dialogue, highlighting not just the scientific advancements, but also the personal philosophies and leade... more

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How many episodes of Innovating Tomorrow's Medicine are there?

Innovating Tomorrow's Medicine launched 6 months ago and published 17 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Innovating Tomorrow's Medicine?

Recent guests on Innovating Tomorrow's Medicine include:

1. David Weitz
2. Pilgrim Jackson
3. Rick Stewart
4. Sheila Gujrathi
5. Rick Fultz
6. Courtney Young
7. Stanley Lewis

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