聊聊Sci
淼淼Elva聊聊Science和Nature！
| Publishes | Daily | Episodes | 469 | Founded | 7 months ago |
|---|---|---|---|---|---|
| Language |  Vietnamese | Number of Listeners | Category | Science |
Listen to this Podcast
Latest Episodes
这项研究通过对384个临床样本进行多组学整合分析，揭示了3型髓母细胞瘤（Group 3 MB）内部显著的代谢异质性。研究人员发现了一种被称为G3p_a的高危蛋白质组亚型，该亚型与MYC癌基因的高表达密切相关，并表现出极差的预后。实验证明，MYC通过促进从头脂质合成与增强脂质摄取，导致肿瘤细胞内脂质滴的大量积聚。这种特殊的脂质依赖性转化为了治疗弱点，特别是针对DGAT1酶的抑制能显著干扰脂质稳态。研究结论指出，靶向脂质代谢通路不仅能延缓肿瘤生长，还为治疗这种极具侵袭性的儿童脑瘤提供了全新的策略。 more
这项由 ARPA-H 发起的 ADAPT 项目 旨在通过 实时监测肿瘤演变 来革新癌症治疗模式。该计划整合了 多模态数据 与 可解释人工智能，构建起一套能够预测耐药性并动态调整方案的临床试验平台。研究重点涵盖 乳腺癌、结直肠癌及肺癌，利用纵向生物标志物精准匹配患者与疗法。通过建立统一的 数据与治疗平台（TAP），全美科研机构可共享病例洞察，实现持续学习。这种 响应式医疗架构 力求在肿瘤发生耐药前进行干预，从而显著提升精准肿瘤学的临床疗效。
References:
• Bild A H, ... more
这项研究通过多组学技术对胆囊癌（GBC）进行了全面的分子图谱绘制，涵盖了基因组、转录组及蛋白质组等多个层面。研究人员识别出ERBB2与ERBB3的新型突变，并揭示了驱动胆囊癌肝转移的关键代谢途径，特别是ACAT1和PHGDH蛋白的促癌作用。通过计算建模，该研究将胆囊癌划分为四种不同的分子亚型，每种亚型具有独特的免疫微环境特征和临床预后。此外，研究还深入探讨了神经内分泌胆囊癌的独特性，发现MEIS1蛋白是诱发腺癌向神经内分泌表型转化的核心调节因子。这些发现为胆囊癌的精准分层和个体化治疗提供了重要的... more
这份研究利用单细胞测序技术（RNA和ATAC测序）深入分析了弥漫性大B细胞淋巴瘤（DLBCL）的分子异质性。研究团队通过对103份活检样本的观测，成功为不同的遗传亚型绘制了独特的基因表达特征。调查发现，大多数肿瘤内部存在由拷贝数变异驱动的遗传亚克隆，这些克隆在细胞分化和生长代谢等方面表现出显著的表型差异。研究重点揭示了 REL基因扩增 如何阻断记忆B细胞的末期分化，从而推动肿瘤发生。最终，这些发现建立了一套关联基因调控网络与临床预后的新模型，为提升化疗和靶向治疗的精准度提供了关键的生物学依据。 more
Reviews
- 我最喜欢的播客之一，谢谢淼淼Elva
One of my favorite podcasts, thanks, 淼淼Elva
Apple Podcasts5TylerZou
China3 months ago - AI生成播客
选题挺好，真人聊就好了
Apple Podcasts1Yuantai SunChina4 months ago
Chart Rankings
How this podcast ranks in the Apple Podcasts, Spotify and YouTube charts.
Apple Podcasts | #30 | China/Science |
Apple Podcasts | #89 |  Hong Kong/Science |
Apple Podcasts | #227 |  Singapore/Science |
Audience Metrics
Listeners, social reach, demographics and more for this podcast.
| Listeners per Episode | Gender Skew | Location | |||
|---|---|---|---|---|---|
| Interests | Professions | Age Range | |||
| Household Income | Social Media Reach | ||||
Frequently Asked Questions About 聊聊Sci
Where can I find podcast stats for 聊聊Sci?
Rephonic provides a wide range of podcast stats for 聊聊Sci. We scanned the web and collated all of the information that we could find in our comprehensive podcast database. See how many people listen to 聊聊Sci and access YouTube viewership numbers, download stats, audience demographics, chart rankings, ratings, reviews and more.
How many listeners does 聊聊Sci get?
Rephonic provides a full set of podcast information for three million podcasts, including the number of listeners. View further listenership figures for 聊聊Sci, including podcast download numbers and subscriber numbers, so you can make better decisions about which podcasts to sponsor or be a guest on. You will need to upgrade your account to access this premium data.
What are the audience demographics for 聊聊Sci?
Rephonic provides comprehensive predictive audience data for 聊聊Sci, including gender skew, age, country, political leaning, income, professions, education level, and interests. You can access these listener demographics by upgrading your account.
How many subscribers and views does 聊聊Sci have?
To see how many followers or subscribers 聊聊Sci has on Spotify and other platforms such as Castbox and Podcast Addict, simply upgrade your account. You'll also find viewership figures for their YouTube channel if they have one.
Which podcasts are similar to 聊聊Sci?
These podcasts share a similar audience with 聊聊Sci:
How many episodes of 聊聊Sci are there?
聊聊Sci launched 7 months ago and published 469 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
How do I contact 聊聊Sci?
Our systems regularly scour the web to find email addresses and social media links for this podcast. We scanned the web and collated all of the contact information that we could find in our podcast database. But in the unlikely event that you can't find what you're looking for, our concierge service lets you request our research team to source better contacts for you.
Where can I see ratings and reviews for 聊聊Sci?
Rephonic pulls ratings and reviews for 聊聊Sci from multiple sources, including Spotify, Apple Podcasts, Castbox, and Podcast Addict.
View all the reviews in one place instead of visiting each platform individually and use this information to decide if a show is worth pitching or not.
How do I access podcast episode transcripts for 聊聊Sci?
Rephonic provides full transcripts for episodes of 聊聊Sci. Search within each transcript for your keywords, whether they be topics, brands or people, and figure out if it's worth pitching as a guest or sponsor. You can even set-up alerts to get notified when your keywords are mentioned.