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Transcribed

Benchling
Drug Development
Drug Discovery
Gene Editing
Cardiovascular Disease
AI and Machine Learning
Kedsila
Genentech
Machine Learning
Schrödinger
Biotechnology Industry
Arc Institute
Verve Therapeutics
Genomic Medicine
Virtual Cell Atlas
Open-Source Models
CRISPR
Her2-Positive Breast Cancer
Sue Desmond-Hellmann
Prostate Cancer
Merck

Transcribed explores the human stories behind biotech breakthroughs. Benchling CEO Sajith Wickramasekara sits down with scientists, founders, and R&D leaders to talk candidly about the decisions shaping modern biotech. From career pivots to breakthroughs, setbacks, and lessons in leadership, these are real conversations with the people moving science forward.

PublishesMonthlyEpisodes5Founded5 months ago
Categories
Life SciencesScienceBusiness

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Latest Episodes

Andrew Bellinger discusses what it takes to build new drug modalities from scratch, the bold bets and tough calls that shaped Verve’s journey, and lessons in building new companies from first-in-class science.

* Editor's note: The interview was reco... more

Jake Becraft reflects on making bold bets in mRNA, the journey from lab bench to biotech founder, and the state of science today.

(00:00) Introduction to Jake Becraft

(00:39) Betting big on mRNA — before it was a proven modality

(11:34) Getting yo... more

Karen Akinsanya unpacks the rise of computational drug discovery, what it takes to prove impact of new technologies, and the importance of setting realistic expectations for AI.

(00:00) Introduction to Karen Akinsanya

(01:54) Pursuing big technolog... more

Sara Kenkare-Mitra talks about resilience, risk, and the kind of leadership it takes to save failing drug programs — and make medicines that matter.

(00:00) Introduction to Sara Kenkare-Mitra

(00:36) Turning a (nearly) failed program into a bestsel... more

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Recent Guests

Karen Akinsanya
President of R&D at Schrödinger, leading drug discovery.
Schrödinger
Episode: Karen Akinsanya on the future of computational drug discovery
Sara Kenkare-Mitra
Former SVP of Development Sciences at Genentech, with over 25 years in R&D
Genentech
Episode: Sara Kenkare-Mitra on saving drug programs and following your curiosity
Patrick Hsu
Co-founder of the Arc Institute and pioneer in CRISPR technology
Episode: Patrick Hsu on betting big: CRISPR, AI, and building science in the open

Host

Sajith Wickramasekara
Host who explores the human stories behind biotech breakthroughs, engaging with scientists, founders, and R&D leaders about the decisions shaping modern biotech.

Chart Rankings

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Apple Podcasts
#171
Israel/Business

Talking Points

Recent interactions between the hosts and their guests.

Karen Akinsanya on the future of computational drug discovery
Q: Was Merck mad at Schrodinger when they already...?
No, they recognized the value and collaboration potential with Schrödinger's computational methodologies.
Karen Akinsanya on the future of computational drug discovery
Q: Can you talk us through this convergence? And what was the tipping point where you knew computational science was the next big disruption for medicine?
Karen reflects on her realization 25 years ago while at Farring Pharmaceuticals about the potential of scaling target identification and highlights her journey through different pharmaceutical roles leading to her focus on computational technologies.
Patrick Hsu on betting big: CRISPR, AI, and building science in the open
Q: What advice would you give to scientists preparing for a career in academia or industry?
Pick a high-impact problem since solving a high-impact problem takes similar effort as a low-impact one.
Patrick Hsu on betting big: CRISPR, AI, and building science in the open
Q: What do you think is going to be the critical factor for lowering cost basis in the rest of the world in the US?
AI and machine learning could bring down certain cost bases significantly.
Patrick Hsu on betting big: CRISPR, AI, and building science in the open
Q: How do you identify those watershed technologies or breakthroughs early on?
By observing patterns and learning from mentors who have been through multiple technological waves.

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Frequently Asked Questions About Transcribed

What is Transcribed about and what kind of topics does it cover?

The content focuses on the innovative landscape of biotechnology, showcasing the experiences and insights of individuals at the forefront of scientific advancements. Topics frequently discussed include gene editing, mRNA technology, drug development, and leadership in the biotech sector. A unique aspect is the emphasis on personal journeys, with guests sharing their challenges and triumphs, making the narratives relatable and engaging for listeners. This intimate exploration of the biotech industry offers valuable lessons not just in science but also in resilience and collaboration, appealing to professionals in the field as well as anyone interested in the human element behind scientific progress.

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These podcasts share a similar audience with Transcribed:

1. Dwarkesh Podcast
2. All-In with Chamath, Jason, Sacks & Friedberg

How many episodes of Transcribed are there?

Transcribed launched 5 months ago and published 5 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.

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What guests have appeared on Transcribed?

Recent guests on Transcribed include:

1. Karen Akinsanya
2. Sara Kenkare-Mitra
3. Patrick Hsu

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