
Adult-onset Still’s disease (AOSD) is a rare, polygenic autoinflammatory syndrome with a pathogenesis similar to systemic juvenile inflammatory arthritis. Join Drs. Petros Efthimiou and Olga Petryna as they discuss making the diagnosis of AOSD through interpretation of clinical and laboratory findings and careful exclusion of other diseases. The faculty review the evidence related to the variety o... more
| Publishes | Daily | Episodes | 4 | Founded | 4 years ago |
|---|---|---|---|---|---|
| Categories | MedicineHealth & Fitness | ||||

* The diagnosis of adult-onset Still’s disease requires extensive evaluation guided by whether systemic or joint signs/symptoms predominate
* Initial disease-modifying therapy with methotrexate is often inadequate to provide symptom relief
* Tr... more
* Goals of treatment: control inflammation, prevent joint and organ damage, minimize treatment-related adverse events; relieve patient burden
* A wide variety of non-biologic and biologic medications are used for treatment, but are supported with ... more
* Adult-onset Still’s disease is a diagnosis of exclusion
* Yamaguchi criteria are useful to classify the disease
* Adult-onset Still’s disease appears to share a similar pathogenesis and disease burden as systemic juvenile inflammatory arthritis
* Viral infection appears to be a common trigger in those with a genetic predisposition, resulting in producing a ... more
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this podcast launched 4 years ago and published 4 episodes to date. You can find more information about this podcast including rankings, audience demographics and engagement in our podcast database.
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